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Analysis of the Polymerization Initiation and Activity of Pasteurella multocida Heparosan Synthase PmHS2, an Enzyme with Glycosyltransferase and UDP-sugar Hydrolase Activity

Heparosan synthase catalyzes the polymerization of heparosan (-4GlcUAβ1–4GlcNAcα1-)(n) by transferring alternatively the monosaccharide units from UDP-GlcUA and UDP-GlcNAc to an acceptor molecule. Details on the heparosan chain initiation by Pasteurella multocida heparosan synthase PmHS2 and its inf...

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Detalhes bibliográficos
Main Authors: Chavaroche, Anais A. E., van den Broek, Lambertus A. M., Springer, Jan, Boeriu, Carmen, Eggink, Gerrit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023472/
https://ncbi.nlm.nih.gov/pubmed/21084307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.136754
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