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Metabolic engineering of Bacillus megaterium for heparosan biosynthesis using Pasteurella multocida heparosan synthase, PmHS2

BACKGROUND: Heparosan is the unsulfated precursor of heparin and heparan sulfate and its synthesis is typically the first step in the production of bioengineered heparin. In addition to its utility as the starting material for this important anticoagulant and anti-inflammatory drug, heparosan is a v...

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Detaylı Bibliyografya
Yayımlandı:Microb Cell Fact
Asıl Yazarlar: Williams, Asher, Gedeon, Kamil S., Vaidyanathan, Deepika, Yu, Yanlei, Collins, Cynthia H., Dordick, Jonathan S., Linhardt, Robert J., Koffas, Mattheos A. G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691538/
https://ncbi.nlm.nih.gov/pubmed/31405374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1187-9
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