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In vitro synthesis of heparosan using recombinant Pasteurella multocida heparosan synthase PmHS2
In vertebrates and bacteria, heparosan the precursor of heparin is synthesized by glycosyltransferases via the stepwise addition of UDP-N-acetylglucosamine and UDP-glucuronic acid. As heparin-like molecules represent a great interest in the pharmaceutical area, the cryptic Pasteurella multocida hepa...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer-Verlag
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811250/ https://ncbi.nlm.nih.gov/pubmed/19756580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-009-2214-2 |
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