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Engineer P. multocida Heparosan Synthase 2 (PmHS2) for Size-Controlled Synthesis of Longer Heparosan Oligosaccharides

Pasteurella multocida heparosan synthase 2 (PmHS2) is a dual-function polysaccharide synthase having both α1–4-N-acetylglucosaminyltransferase (α1–4-GlcNAcT) and β1–4-glucuronyltransferase (β1–4-GlcAT) activities located in two separate catalytic domains. We found that removing PmHS2 N-terminal 80-a...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Na, Lan, Yu, Hai, McArthur, John B., Ghosh, Tamashree, Asbell, Thomas, Chen, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842274/
https://ncbi.nlm.nih.gov/pubmed/33520345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c01231
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