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Structure/Function Analysis of Pasteurella multocida Heparosan Synthases: TOWARD DEFINING ENZYME SPECIFICITY AND ENGINEERING NOVEL CATALYSTS
The Pasteurella multocida heparosan synthases, PmHS1 and PmHS2, are homologous (∼65% identical) bifunctional glycosyltransferase proteins found in Type D Pasteurella. These unique enzymes are able to generate the glycosaminoglycan heparosan by polymerizing sugars to form repeating disaccharide units...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293577/ https://ncbi.nlm.nih.gov/pubmed/22235128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311704 |
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