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Structure/Function Analysis of Pasteurella multocida Heparosan Synthases: TOWARD DEFINING ENZYME SPECIFICITY AND ENGINEERING NOVEL CATALYSTS

The Pasteurella multocida heparosan synthases, PmHS1 and PmHS2, are homologous (∼65% identical) bifunctional glycosyltransferase proteins found in Type D Pasteurella. These unique enzymes are able to generate the glycosaminoglycan heparosan by polymerizing sugars to form repeating disaccharide units...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Otto, Nigel J., Green, Dixy E., Masuko, Sayaka, Mayer, Alain, Tanner, Martin E., Linhardt, Robert J., DeAngelis, Paul L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293577/
https://ncbi.nlm.nih.gov/pubmed/22235128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311704
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