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Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles

RNA interference (RNAi) has an unprecedented potential as a therapeutic strategy for reversibly silencing the expression of any gene. Therapeutic delivery of the RNAi mediator, i.e., small interfering RNA (siRNA), can be used to address diseases characterized by gene overexpression, for example infl...

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Xehetasun bibliografikoak
Argitaratua izan da:Front Bioeng Biotechnol
Egile Nagusiak: Lokras, Abhijeet, Thakur, Aneesh, Wadhwa, Abishek, Thanki, Kaushik, Franzyk, Henrik, Foged, Camilla
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841370/
https://ncbi.nlm.nih.gov/pubmed/33520957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.601155
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