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Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model

To improve the efficacy of nucleic acid-based therapeutics, e.g., small interfering RNA (siRNA), transfection agents are needed for efficient delivery into cells. Several classes of dendrimers have been found useful as transfection agents for the delivery of siRNA because their surface can readily b...

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Podrobná bibliografie
Vydáno v:Eur J Pharm Biopharm
Hlavní autoři: Bohr, Adam, Tsapis, Nicolas, Foged, Camilla, Andreana, Ilaria, Yang, Mingshi, Fattal, Elias
Médium: Artigo
Jazyk:Inglês
Vydáno: Published by Elsevier B.V. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425770/
https://ncbi.nlm.nih.gov/pubmed/32798665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2020.08.009
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