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In‐Cell NMR Spectroscopy of Functional Riboswitch Aptamers in Eukaryotic Cells
We report here the in‐cell NMR‐spectroscopic observation of the binding of the cognate ligand 2′‐deoxyguanosine to the aptamer domain of the bacterial 2′‐deoxyguanosine‐sensing riboswitch in eukaryotic cells, namely Xenopus laevis oocytes and in human HeLa cells. The riboswitch is sufficiently stabl...
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| 出版年: | Angew Chem Int Ed Engl |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7839747/ https://ncbi.nlm.nih.gov/pubmed/32975353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202007184 |
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