Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy

The full-length translation-regulating add adenine riboswitch (Asw) from Vibrio vulnificus has a more complex conformational space than its isolated aptamer domain. In addition to the predicted apo (apoA) and holo conformation that feature the conserved three-way junctional purine riboswitch aptamer...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Warhaut, Sven, Mertinkus, Klara Rebecca, Höllthaler, Philipp, Fürtig, Boris, Heilemann, Mike, Hengesbach, Martin, Schwalbe, Harald
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605240/
https://ncbi.nlm.nih.gov/pubmed/28204648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx110
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