Engineered SAM Synthetases for Enzymatic Generation of AdoMet Analogs with Photocaging Groups and Reversible DNA Modification in Cascade Reactions

Methylation and demethylation of DNA, RNA and proteins has emerged as a major regulatory mechanism. Studying the function of these modifications would benefit from tools for their site‐specific inhibition and timed removal. S‐Adenosyl‐L‐methionine (AdoMet) analogs in combination with methyltransfera...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Angew Chem Int Ed Engl
Main Authors: Michailidou, Freideriki, Klöcker, Nils, Cornelissen, Nicolas V., Singh, Rohit K., Peters, Aileen, Ovcharenko, Anna, Kümmel, Daniel, Rentmeister, Andrea
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839696/
https://ncbi.nlm.nih.gov/pubmed/33017502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202012623
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki