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Nucleoside-modified AdoMet analogues for differential methyltransferase targeting

Methyltransferases (MTases) modify a wide range of biomolecules using S-adenosyl-L-methionine (AdoMet) as cosubstrate. Synthetic AdoMet analogues are powerful tools to site-specifically introduce a variety of functional groups and bear potential to be converted only by distinct MTases. Extending the...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Cornelissen, Nicolas V., Michailidou, Freideriki, Muttach, Fabian, Rau, Kristina, Rentmeister, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030947/
https://ncbi.nlm.nih.gov/pubmed/31970375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc07807j
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