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Complementation of a metK-deficient E. coli strain with heterologous AdoMet synthetase genes

S-adenosyl-l-methionine (AdoMet) is an essential metabolite, playing a wide variety of metabolic roles. The enzyme that produces AdoMet from l-methionine and ATP (methionine adenosyltransferase, MAT) is thus an attractive target for anti-cancer and antimicrobial agents. It would be very useful to ha...

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Publicat a:Microbiology (Reading)
Autors principals: Parungao, Gwenn G., Zhao, Mojun, Wang, Qinzhe, Zano, Stephen P., Viola, Ronald E., Blumenthal, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Microbiology Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845735/
https://ncbi.nlm.nih.gov/pubmed/29111970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000565
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