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Structural Diversity in the AdoMet Radical Enzyme Superfamily

AdoMet radical enzymes are involved in processes such as cofactor biosynthesis, anaerobic metabolism, and natural product biosynthesis. These enzymes utilize the reductive cleavage of S-adenosylmethionine (AdoMet) to afford L-methionine and a transient 5'-deoxyadenosyl radical, which subsequent...

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Autores principales: Dowling, Daniel P., Vey, Jessica L., Croft, Anna K., Drennan, Catherine L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523193/
https://ncbi.nlm.nih.gov/pubmed/22579873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2012.04.006
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