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Radical Reaction Control in the AdoMet Radical Enzyme CDG Synthase (QueE): Consolidate, Destabilize, Accelerate

Controlling radical intermediates and thus catalysing and directing complex radical reactions is a central feature of S‐adensosylmethionine (SAM)‐dependent radical enzymes. We report ab initio and DFT calculations highlighting the specific influence of ion complexation, including Mg(2+), identified...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Jäger, Christof M., Croft, Anna K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347944/
https://ncbi.nlm.nih.gov/pubmed/27859789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201604719
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