Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as α7 nAChRs Positive Allosteric Modulators

The α7 nicotinic acetylcholine receptor (α7 nAChR) is a ligand-gated ion channel that is involved in cognition disorders, schizophrenia, pain, and inflammation. Allosteric modulation of this receptor might be advantageous to reduce the toxicity in comparison with full agonists. Our previous results...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Ximenis, Marta, Mulet, José, Sala, Salvador, Sala, Francisco, Criado, Manuel, González-Muñiz, Rosario, Pérez de Vega, María Jesús
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835927/
https://ncbi.nlm.nih.gov/pubmed/33478095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020973
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