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Semisynthetic Analogues of Toxiferine I and Their Pharmacological Properties at α7 nAChRs, Muscle-Type nAChRs, and the Allosteric Binding Site of Muscarinic M(2) Receptors

[Image: see text] A new series of analogues of the calabash curare alkaloid toxiferine I was prepared and pharmacologically evaluated at α7 and muscle-type nAChRs and the allosteric site of muscarinic M(2) receptors. The new ligands differ from toxiferine I by the absence of one (2a–c) or two (3a–c)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zlotos, Darius P., Tränkle, Christian, Holzgrabe, Ulrike, Gündisch, Daniela, Jensen, Anders A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society and American Society of Pharmacognosy 2014
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176391/
https://ncbi.nlm.nih.gov/pubmed/25192059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500259j
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