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Pathological ATX3 Expression Induces Cell Perturbations in E. coli as Revealed by Biochemical and Biophysical Investigations

Amyloid aggregation of human ataxin-3 (ATX3) is responsible for spinocerebellar ataxia type 3, which belongs to the class of polyglutamine neurodegenerative disorders. It is widely accepted that the formation of toxic oligomeric species is primarily involved in the onset of the disease. For this rea...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Ami, Diletta, Sciandrone, Barbara, Mereghetti, Paolo, Falvo, Jacopo, Catelani, Tiziano, Visentin, Cristina, Tortora, Paolo, Ventura, Salvador, Natalello, Antonino, Regonesi, Maria Elena
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835732/
https://ncbi.nlm.nih.gov/pubmed/33477953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020943
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