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Pathological ATX3 Expression Induces Cell Perturbations in E. coli as Revealed by Biochemical and Biophysical Investigations

Amyloid aggregation of human ataxin-3 (ATX3) is responsible for spinocerebellar ataxia type 3, which belongs to the class of polyglutamine neurodegenerative disorders. It is widely accepted that the formation of toxic oligomeric species is primarily involved in the onset of the disease. For this rea...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ami, Diletta, Sciandrone, Barbara, Mereghetti, Paolo, Falvo, Jacopo, Catelani, Tiziano, Visentin, Cristina, Tortora, Paolo, Ventura, Salvador, Natalello, Antonino, Regonesi, Maria Elena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835732/
https://ncbi.nlm.nih.gov/pubmed/33477953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020943
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