3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

Transit-amplifying nephron progenitor cells (NPCs) generate all of the nephrons of the mammalian kidney during development. Their limited numbers, poor in vitro expansion, and difficult accessibility in humans have slowed basic and translational research into renal development and diseases. Here, we...

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Publicado en:Cell Stem Cell
Autores principales: Li, Zhongwei, Araoka, Toshikazu, Wu, Jun, Liao, Hsin-Kai, Li, Mo, Lazo, Marta, Zhou, Bing, Sui, Yinghui, Wu, Min-Zu, Tamura, Isao, Xia, Yun, Beyret, Ergin, Matsusaka, Taiji, Pastan, Ira, Esteban, Concepcion Rodriguez, Guillen, Isabel, Guillen, Pedro, Campistol, Josep M., Belmonte, Juan Carlos Izpisua
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832086/
https://ncbi.nlm.nih.gov/pubmed/27570066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.07.016
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