3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

Transit-amplifying nephron progenitor cells (NPCs) generate all of the nephrons of the mammalian kidney during development. Their limited numbers, poor in vitro expansion, and difficult accessibility in humans have slowed basic and translational research into renal development and diseases. Here, we...

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Veröffentlicht in:Cell Stem Cell
Hauptverfasser: Li, Zhongwei, Araoka, Toshikazu, Wu, Jun, Liao, Hsin-Kai, Li, Mo, Lazo, Marta, Zhou, Bing, Sui, Yinghui, Wu, Min-Zu, Tamura, Isao, Xia, Yun, Beyret, Ergin, Matsusaka, Taiji, Pastan, Ira, Esteban, Concepcion Rodriguez, Guillen, Isabel, Guillen, Pedro, Campistol, Josep M., Belmonte, Juan Carlos Izpisua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832086/
https://ncbi.nlm.nih.gov/pubmed/27570066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.07.016
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