3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

Transit-amplifying nephron progenitor cells (NPCs) generate all of the nephrons of the mammalian kidney during development. Their limited numbers, poor in vitro expansion, and difficult accessibility in humans have slowed basic and translational research into renal development and diseases. Here, we...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Li, Zhongwei, Araoka, Toshikazu, Wu, Jun, Liao, Hsin-Kai, Li, Mo, Lazo, Marta, Zhou, Bing, Sui, Yinghui, Wu, Min-Zu, Tamura, Isao, Xia, Yun, Beyret, Ergin, Matsusaka, Taiji, Pastan, Ira, Esteban, Concepcion Rodriguez, Guillen, Isabel, Guillen, Pedro, Campistol, Josep M., Belmonte, Juan Carlos Izpisua
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832086/
https://ncbi.nlm.nih.gov/pubmed/27570066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.07.016
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