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Cellular Uptake and Cytosolic Delivery of a Cyclic Cystine Knot Scaffold

Cyclotides are macrocyclic peptides with exceptionally stable structures and have been reported to penetrate cells, making them promising scaffolds for the delivery of inhibitory peptides to target intracellular proteins. However, their cellular uptake and cytosolic localization have been poorly und...

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Dades bibliogràfiques
Publicat a:ACS Chem Biol
Autors principals: Yin, Huawu, Huang, Yen-Hua, Deprey, Kirsten, Condon, Nicholas D., Kritzer, Joshua A., Craik, David J., Wang, Conan K.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831380/
https://ncbi.nlm.nih.gov/pubmed/32315152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00297
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