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Quantitative measurement of cytosolic penetration using the Chloroalkane Penetration Assay
A major barrier for drug development is ensuring molecules can access intracellular targets. This is especially true for biomolecules, which are notoriously difficult to deliver to the cytosol. Many current methods for measuring the internalization of therapeutic biomolecules are largely indirect an...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7872221/ https://ncbi.nlm.nih.gov/pubmed/32713526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2020.03.003 |
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