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Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay

Cytosolic transport is an essential requirement but a major obstacle to efficient delivery of therapeutic peptides, proteins and nucleic acids. Current understanding of cytosolic delivery mechanisms remains limited due to a significant number of conflicting reports, which are compounded by low sensi...

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Vydáno v:Nat Commun
Hlavní autoři: Teo, Serena L. Y., Rennick, Joshua J., Yuen, Daniel, Al-Wassiti, Hareth, Johnston, Angus P. R., Pouton, Colin W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211857/
https://ncbi.nlm.nih.gov/pubmed/34140497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23997-x
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