Cytosolic delivery of macromolecules in live human cells using the combined endosomal escape activities of a small molecule and cell penetrating peptides

Ineffective cellular delivery is a common problem in numerous biological applications. Developing delivery reagents that work robustly in a variety of experimental settings remains a challenge. Herein, we report how peptides derived from the prototypical cell penetrating peptide TAT can be used in c...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Allen, Jason, Najjar, Kristina, Erazo-Oliveras, Alfredo, Kondow-McConaghy, Helena M., Brock, Dakota J., Graham, Kristin, Hager, Elizabeth C., Marschall, Andrea L. J., Dübel, Stefan, Juliano, Rudolph L., Pellois, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008471/
https://ncbi.nlm.nih.gov/pubmed/31633910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00585
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