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Cell Penetration Profiling Using the Chloroalkane Penetration Assay

Biotherapeutics are a promising class of molecules in drug discovery, but they are often limited to extracellular targets due to their poor cell penetration. High-throughput cell penetration assays are required for the optimization of biotherapeutics for enhanced cell penetration. We developed a Hal...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Peraro, Leila, Deprey, Kirsten L., Moser, Matthew K., Zou, Zhongju, Ball, Haydn L., Levine, Beth, Kritzer, Joshua A.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205923/
https://ncbi.nlm.nih.gov/pubmed/30118219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b06144
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