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Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy

[Image: see text] Autophagy is an essential pathway by which cellular and foreign material are degraded and recycled in eukaryotic cells. Induction of autophagy is a promising approach for treating diverse human diseases, including neurodegenerative disorders and infectious diseases. Here, we report...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Peraro, Leila, Zou, Zhongju, Makwana, Kamlesh M., Cummings, Ashleigh E., Ball, Haydn L., Yu, Hongtao, Lin, Yu-Shan, Levine, Beth, Kritzer, Joshua A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473019/
https://ncbi.nlm.nih.gov/pubmed/28414223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01698
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