A Cell-Penetrant Lactam-Stapled Peptide for Targeting eIF4E Protein-Protein Interactions

Eukaryotic translation initiation factor 4E (eIF4E) has emerged as a promising cancer therapeutic target due to its role in the initiation of cap-dependent translation, a process that is accelerated during tumorigenesis. To regulate the initiation of cap-dependent translation, eIF4E participates in...

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Bibliographic Details
Published in:Eur J Med Chem
Main Authors: Gallagher, Erin E., Menon, Arya, Chmiel, Alyah F., Deprey, Kirsten, Kritzer, Joshua A., Garner, Amanda L.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541464/
https://ncbi.nlm.nih.gov/pubmed/32739551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112655
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