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Cellular Uptake and Cytosolic Delivery of a Cyclic Cystine Knot Scaffold

Cyclotides are macrocyclic peptides with exceptionally stable structures and have been reported to penetrate cells, making them promising scaffolds for the delivery of inhibitory peptides to target intracellular proteins. However, their cellular uptake and cytosolic localization have been poorly und...

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Библиографические подробности
Опубликовано в: :ACS Chem Biol
Главные авторы: Yin, Huawu, Huang, Yen-Hua, Deprey, Kirsten, Condon, Nicholas D., Kritzer, Joshua A., Craik, David J., Wang, Conan K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831380/
https://ncbi.nlm.nih.gov/pubmed/32315152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00297
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