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Cellular Uptake and Cytosolic Delivery of a Cyclic Cystine Knot Scaffold

Cyclotides are macrocyclic peptides with exceptionally stable structures and have been reported to penetrate cells, making them promising scaffolds for the delivery of inhibitory peptides to target intracellular proteins. However, their cellular uptake and cytosolic localization have been poorly und...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Yin, Huawu, Huang, Yen-Hua, Deprey, Kirsten, Condon, Nicholas D., Kritzer, Joshua A., Craik, David J., Wang, Conan K.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831380/
https://ncbi.nlm.nih.gov/pubmed/32315152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00297
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