DNA Methylation Levels in Mononuclear Leukocytes from the Mother and Her Child Are Associated with IgE Sensitization to Allergens in Early Life

DNA methylation changes may predispose becoming IgE-sensitized to allergens. We analyzed whether DNA methylation in peripheral blood mononuclear cells (PBMC) is associated with IgE sensitization at 5 years of age (5Y). DNA methylation was measured in 288 PBMC samples from 74 mother/child pairs from...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Acevedo, Nathalie, Scala, Giovanni, Merid, Simon Kebede, Frumento, Paolo, Bruhn, Sören, Andersson, Anna, Ogris, Christoph, Bottai, Matteo, Pershagen, Göran, Koppelman, Gerard H., Melén, Erik, Sonnhammer, Erik, Alm, Johan, Söderhäll, Cilla, Kere, Juha, Greco, Dario, Scheynius, Annika
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830007/
https://ncbi.nlm.nih.gov/pubmed/33466918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020801
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