Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC

SIMPLE SUMMARY: Hepatocellular carcinoma (HCC) represents the most common type of liver cancer and has a poor prognosis. Therefore, there is an urgent need for the identification of new therapeutic options. The mouse double minute homolog 4 (MDM4) gene, a known p53 inhibitor, is upregulated in most...

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Pubblicato in:Cancers (Basel)
Autori principali: Pellegrino, Rossella, Thavamani, Abhishek, Calvisi, Diego F., Budczies, Jan, Neumann, Ariane, Geffers, Robert, Kroemer, Jasmin, Greule, Damaris, Schirmacher, Peter, Nordheim, Alfred, Longerich, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7829828/
https://ncbi.nlm.nih.gov/pubmed/33429878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020199
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