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The Proto-Oncogene Function of Mdm2 in Bone

Mouse double minute 2 (Mdm2) is a multifaceted oncoprotein that is highly regulated with distinct domains capable of cellular transformation. Loss of Mdm2 is embryonically lethal, making it difficult to study in a mouse model without additional genetic alterations. Global overexpression through incr...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Olivos, David J., Perrien, Daniel S., Hooker, Adam, Cheng, Ying-Hua, Fuchs, Robyn K., Hong, Jung Min, Bruzzaniti, Angela, Chun, Kristin, Eischen, Christine M., Kacena, Melissa A., Mayo, Lindsey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348883/
https://ncbi.nlm.nih.gov/pubmed/30011084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.27133
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