Pyk2 Regulates Megakaryocyte-Induced Increases in Osteoblast Number and Bone Formation

Pre-clinical and clinical evidence from megakaryocyte (MK) related diseases suggest that MKs play a significant role in maintaining bone homeostasis. Findings from our laboratories reveal that MKs significantly increase osteoblast (OB) number through direct MK-OB contact and the activation of integr...

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Autores principales: Cheng, Ying-Hua, Hooker, R. Adam, Nguyen, Khanh, Gerard-O’Riley, Rita, Waning, David L., Chitteti, Brahmananda R., Meijome, Tomas E., Chua, Hui Lin, Plett, Artur P., Orschell, Christie M., Srour, Edward F., Mayo, Lindsey D., Pavalko, Fredrick M., Bruzzaniti, Angela, Kacena, Melissa A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663900/
https://ncbi.nlm.nih.gov/pubmed/23362087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1876
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