Haplotype structure and selection of the MDM2 oncogene in humans

The MDM2 protein is an ubiquitin ligase that plays a critical role in regulating the levels and activity of the p53 protein, which is a central tumor suppressor. A SNP in the human MDM2 gene (SNP309 T/G) occurs at frequencies dependent on demographic history and has been shown to have important diff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Atwal, Gurinder Singh, Bond, Gareth L., Metsuyanim, Sally, Papa, Moshe, Friedman, Eitan, Distelman-Menachem, Tal, Ben Asher, Edna, Lancet, Doron, Ross, David A., Sninsky, John, White, Tomas J., Levine, Arnold J., Yarden, Ronit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Physical Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838634/
https://ncbi.nlm.nih.gov/pubmed/17360557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610998104
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg