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p53, A Victim of the Prion Fashion

SIMPLE SUMMARY: The tumor suppressor gene TP53 is found mutated in around half of human cancers. The accumulation of the mutant p53 protein in the form of aggregates in cancer cells have led to the emergence of the “prion p53” hypothesis which states that mutant p53 is able to drive the wild-type fo...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Billant, Olivier, Friocourt, Gaëlle, Roux, Pierre, Voisset, Cécile
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828285/
https://ncbi.nlm.nih.gov/pubmed/33450819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020269
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