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p53, A Victim of the Prion Fashion
SIMPLE SUMMARY: The tumor suppressor gene TP53 is found mutated in around half of human cancers. The accumulation of the mutant p53 protein in the form of aggregates in cancer cells have led to the emergence of the “prion p53” hypothesis which states that mutant p53 is able to drive the wild-type fo...
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| 出版年: | Cancers (Basel) |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7828285/ https://ncbi.nlm.nih.gov/pubmed/33450819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020269 |
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