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p53, A Victim of the Prion Fashion

SIMPLE SUMMARY: The tumor suppressor gene TP53 is found mutated in around half of human cancers. The accumulation of the mutant p53 protein in the form of aggregates in cancer cells have led to the emergence of the “prion p53” hypothesis which states that mutant p53 is able to drive the wild-type fo...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Billant, Olivier, Friocourt, Gaëlle, Roux, Pierre, Voisset, Cécile
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828285/
https://ncbi.nlm.nih.gov/pubmed/33450819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020269
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