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The dominant-negative interplay between p53, p63 and p73: A family affair
The tumor suppression activity of p53 is frequently impaired in cancers even when a wild-type copy of the gene is still present, suggesting that a dominant-negative effect is exerted by some of p53 mutants and isoforms. p63 and p73, which are related to p53, have also been reported to be subjected t...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342497/ https://ncbi.nlm.nih.gov/pubmed/27589690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11774 |
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