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p53, A Victim of the Prion Fashion

SIMPLE SUMMARY: The tumor suppressor gene TP53 is found mutated in around half of human cancers. The accumulation of the mutant p53 protein in the form of aggregates in cancer cells have led to the emergence of the “prion p53” hypothesis which states that mutant p53 is able to drive the wild-type fo...

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Publicat a:Cancers (Basel)
Autors principals: Billant, Olivier, Friocourt, Gaëlle, Roux, Pierre, Voisset, Cécile
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828285/
https://ncbi.nlm.nih.gov/pubmed/33450819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020269
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