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p53, A Victim of the Prion Fashion
SIMPLE SUMMARY: The tumor suppressor gene TP53 is found mutated in around half of human cancers. The accumulation of the mutant p53 protein in the form of aggregates in cancer cells have led to the emergence of the “prion p53” hypothesis which states that mutant p53 is able to drive the wild-type fo...
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| Pubblicato in: | Cancers (Basel) |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7828285/ https://ncbi.nlm.nih.gov/pubmed/33450819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020269 |
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