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The dominant-negative interplay between p53, p63 and p73: A family affair
The tumor suppression activity of p53 is frequently impaired in cancers even when a wild-type copy of the gene is still present, suggesting that a dominant-negative effect is exerted by some of p53 mutants and isoforms. p63 and p73, which are related to p53, have also been reported to be subjected t...
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| Vydáno v: | Oncotarget |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342497/ https://ncbi.nlm.nih.gov/pubmed/27589690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11774 |
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