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Customized optical mapping by CRISPR–Cas9 mediated DNA labeling with multiple sgRNAs
Whole-genome mapping technologies have been developed as a complementary tool to provide scaffolds for genome assembly and structural variation analysis (1,2). We recently introduced a novel DNA labeling strategy based on a CRISPR–Cas9 genome editing system, which can target any 20bp sequences. The...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7826249/ https://ncbi.nlm.nih.gov/pubmed/33231685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1088 |
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