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Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system

Visualization of chromosomal dynamics is important for understanding many fundamental intra-nuclear processes. Efficient and reliable live-cell multicolor labeling of chromosomal loci can realize this goal. However, the current methods are constrained mainly by insufficient labeling throughput, effi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Shao, Shipeng, Zhang, Weiwei, Hu, Huan, Xue, Boxin, Qin, Jinshan, Sun, Chaoying, Sun, Yuao, Wei, Wensheng, Sun, Yujie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872083/
https://ncbi.nlm.nih.gov/pubmed/26850639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw066
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