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Splicing factor SRSF1 controls T cell homeostasis and its decreased levels are linked to lymphopenia in systemic lupus erythematosus

OBJECTIVE: Lymphopenia is a frequent clinical manifestation and risk factor for infections in SLE, but the underlying mechanisms are not fully understood. We previously identified novel roles for the RNA-binding protein serine arginine-rich splicing factor 1 (SRSF1) in the control of genes involved...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: Katsuyama, Takayuki, Martin-Delgado, Ignacio Juarez, Krishfield, Suzanne M, Kyttaris, Vasileios C, Moulton, Vaishali R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825486/
https://ncbi.nlm.nih.gov/pubmed/32206811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keaa094
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