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Downregulation of CD3ζ in Natural Killer Cells from Systemic Lupus Erythematosus Patients Confers a Pro-Inflammatory Phenotype
Cytotoxic function and cytokine profile of natural killer cells are compromised in patients with systemic lupus erythematosus (SLE). CD3ζ, an important molecule for NK cell activation, is downregulated in SLE T cells and contributes to their altered function. However, little is known about the role...
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| Publicado en: | J Immunol |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048443/ https://ncbi.nlm.nih.gov/pubmed/29602774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700588 |
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