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Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity

Systemic lupus erythematosus (SLE) is a devastating autoimmune disease in which hyperactive T cells play a critical role. Understanding molecular mechanisms underlying the T cell hyperactivity will lead to identification of specific therapeutic targets. Serine/arginine-rich splicing factor 1 (SRSF1)...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Katsuyama, Takayuki, Li, Hao, Comte, Denis, Tsokos, George C., Moulton, Vaishali R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877308/
https://ncbi.nlm.nih.gov/pubmed/31487268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127949
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