Transferability of N-terminal mutations of pyrrolysyl-tRNA synthetase in one species to that in another species on unnatural amino acid incorporation efficiency

Genetic code expansion is a powerful technique for site-specific incorporation of an unnatural amino acid into a protein of interest. This technique relies on an orthogonal aminoacyl-tRNA synthetase/tRNA pair and has enabled incorporation of over 100 different unnatural amino acids into ribosomally...

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Bibliographic Details
Published in:Amino Acids
Main Authors: Williams, Thomas L., Iskandar, Debra J., Nödling, Alexander R., Tan, Yurong, Luk, Louis Y. P., Tsai, Yu-Hsuan
Format: Artigo
Language:Inglês
Published: Springer Vienna 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822784/
https://ncbi.nlm.nih.gov/pubmed/33331978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-020-02927-z
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