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Expanding the Library and Substrate Diversity of the Pyrrolysyl-tRNA Synthetase to Incorporate Unnatural Amino Acids Containing Conjugated Rings

Unnatural amino acids (Uaas) containing conjugated ring systems are of particular interest for their optical properties. Until now, such structurally bulky and planar Uaas could not be incorporated into proteins using the pyrrolsyl tRNA/synthetase shuttling system. By building a highly diverse synth...

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Detalhes bibliográficos
Main Authors: Lacey, Vanessa K., Louie, Gordon V., Noel, Joseph P., Wang, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947478/
https://ncbi.nlm.nih.gov/pubmed/24019075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300400
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