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Expanding the Library and Substrate Diversity of the Pyrrolysyl-tRNA Synthetase to Incorporate Unnatural Amino Acids Containing Conjugated Rings
Unnatural amino acids (Uaas) containing conjugated ring systems are of particular interest for their optical properties. Until now, such structurally bulky and planar Uaas could not be incorporated into proteins using the pyrrolsyl tRNA/synthetase shuttling system. By building a highly diverse synth...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947478/ https://ncbi.nlm.nih.gov/pubmed/24019075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300400 |
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