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Structure‐based non‐nucleoside inhibitor design: Developing inhibitors that are effective against resistant mutants
Non‐nucleoside reverse transcriptase inhibitors (NNRTIs) inhibit reverse transcription and block the replication of HIV‐1. Currently, NNRTIs are usually used as part of a three‐drug combination given to patients as antiretroviral therapy. These combinations involve other classes of anti‐HIV‐1 drugs,...
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| Vydáno v: | Chem Biol Drug Des |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7821153/ https://ncbi.nlm.nih.gov/pubmed/32743937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13766 |
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